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General Medicine · Cardiology
Sample itemWhich feature is most concerning for infective endocarditis in a patient with persistent fever?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. A new cardiac murmur with positive blood cultures
Persistent bacteraemia together with a new or changing murmur suggests infective endocarditis, where repeated blood cultures and echocardiography help establish diagnosis and guide prolonged antimicrobial or surgical management.
Option by option
A. A stable childhood birthmark
A stable birthmark does not indicate bloodstream infection or valve disease.
B. A healed ankle sprain
A healed sprain is unrelated to infective endocarditis.
C. Isolated seasonal rhinitis
Seasonal rhinitis is an allergic upper-airway condition.
D. A new cardiac murmur with positive blood cultures (correct)
Correct: positive cultures plus a new murmur are important endocarditis clues.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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