Coagulation disorders: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

Try it

Pathology · Coagulation disorders

Sample item

What process best explains simultaneous bleeding and microvascular thrombosis in disseminated intravascular coagulation?

AOnly reduced red-cell productionBSimple dehydration without inflammationCWidespread coagulation activation consuming platelets and factorsDIsolated vitamin C deficiency

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Widespread coagulation activation consuming platelets and factors

Disseminated intravascular coagulation involves pathologic systemic coagulation activation, generating microthrombi while consuming platelets and clotting factors, which can then produce serious bleeding and organ dysfunction.

Option by option

A. Only reduced red-cell production
Reduced erythropoiesis causes anaemia, not DIC physiology.
B. Simple dehydration without inflammation
Dehydration alone does not explain this combined thrombosis and bleeding syndrome.
C. Widespread coagulation activation consuming platelets and factors (correct)
Correct: consumption of platelets and factors follows widespread clotting activation.
D. Isolated vitamin C deficiency
Vitamin C deficiency causes connective-tissue bleeding but not diffuse microthrombosis.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is C, Widespread coagulation activation consuming platelets and factors. Disseminated intravascular coagulation involves pathologic systemic coagulation activation, generating microthrombi while consuming platelets and clotting factors, which can then produce serious bleeding and organ dysfunction.

Why is "Only reduced red-cell production" not the answer?

Reduced erythropoiesis causes anaemia, not DIC physiology.

Why is "Simple dehydration without inflammation" not the answer?

Dehydration alone does not explain this combined thrombosis and bleeding syndrome.

Why is "Isolated vitamin C deficiency" not the answer?

Vitamin C deficiency causes connective-tissue bleeding but not diffuse microthrombosis.

What concept does this question test?

It tests Coagulation disorders in Pathology. The correct option holds because: Correct: consumption of platelets and factors follows widespread clotting activation.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Coagulation disorders?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.