Cell injury: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Cell injury

Sample item

Which feature is most typical of apoptosis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Cell shrinkage with membrane-bound fragments

Apoptosis is programmed cell death featuring cell shrinkage and membrane-bound apoptotic bodies that are cleared with little surrounding inflammation.

Option by option

  • A. Massive intracellular oedema only

    Oedema alone is not the defining feature.

  • B. Diffuse tissue inflammation from rupture

    Cell rupture and inflammation are more typical necrosis.

  • C. Formation of pus in every case

    Pus formation requires a particular inflammatory context.

  • D. Cell shrinkage with membrane-bound fragments (correct)

    Correct: orderly cell fragmentation is typical apoptosis.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is D, Cell shrinkage with membrane-bound fragments. Apoptosis is programmed cell death featuring cell shrinkage and membrane-bound apoptotic bodies that are cleared with little surrounding inflammation.

Why is "Massive intracellular oedema only" not the answer?

Oedema alone is not the defining feature.

Why is "Diffuse tissue inflammation from rupture" not the answer?

Cell rupture and inflammation are more typical necrosis.

Why is "Formation of pus in every case" not the answer?

Pus formation requires a particular inflammatory context.

What concept does this question test?

It tests Cell injury in Pathology. The correct option holds because: Correct: orderly cell fragmentation is typical apoptosis.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Cell injury?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.