Cell injury: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

Try it

Pathology · Cell injury

Sample item

What is the defining feature of necrosis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Uncontrolled cell death with membrane disruption

Necrosis is uncontrolled cell death with loss of membrane integrity and release of cellular contents, often provoking inflammation in surrounding tissue.

Option by option

  • A. Uncontrolled cell death with membrane disruption (correct)

    Correct: membrane breakdown and inflammation characterize necrosis.

  • B. Programmed cell removal without inflammation

    Apoptosis is regulated cell death with limited inflammation.

  • C. Reversible cell swelling only

    Reversible swelling occurs before irreversible necrosis.

  • D. Normal cellular division

    Cell division is proliferation, not death.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is A, Uncontrolled cell death with membrane disruption. Necrosis is uncontrolled cell death with loss of membrane integrity and release of cellular contents, often provoking inflammation in surrounding tissue.

Why is "Programmed cell removal without inflammation" not the answer?

Apoptosis is regulated cell death with limited inflammation.

Why is "Reversible cell swelling only" not the answer?

Reversible swelling occurs before irreversible necrosis.

Why is "Normal cellular division" not the answer?

Cell division is proliferation, not death.

What concept does this question test?

It tests Cell injury in Pathology. The correct option holds because: Correct: membrane breakdown and inflammation characterize necrosis.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Cell injury?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.