Protein deposition disorders: practice question

The best answer is A, Apple-green birefringence. Amyloid deposits bind Congo red and show apple-green birefringence under polarized light, a characteristic demonstration of abnormal extracellular fibrillar protein accumulation in affected tissues.

Acid-fast red bacilli indicate mycobacterial staining, not amyloid.

Blue-black nuclear staining describes different histologic techniques.

Gram-positive cocci are bacteria seen with Gram stain, not protein deposits.

It tests Protein deposition disorders in Pathology. The correct option holds because: Correct: apple-green birefringence is the classic Congo-red amyloid finding.

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.