Wound healing: granulation tissue: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

Try it

Pathology · Wound healing: granulation tissue

Sample item

Which histologic combination best defines granulation tissue in a healing wound?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. New capillaries, proliferating fibroblasts and loose extracellular matrix

Granulation tissue is the vascular, fibroblast-rich repair tissue that fills a wound during the proliferative phase. It later remodels into a less vascular collagenous scar.

Option by option

  • A. Sheets of neutrophils and liquefactive necrosis

    This describes acute suppurative injury, not repair.

  • B. Mature cartilage and bone

    Cartilage and bone are not normal components of cutaneous granulation tissue.

  • C. Dense hypocellular collagen with no vessels

    Dense, low-cellularity collagen characterises a mature scar.

  • D. New capillaries, proliferating fibroblasts and loose extracellular matrix (correct)

    Correct. Angiogenesis and fibroblast proliferation are the core features.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is D, New capillaries, proliferating fibroblasts and loose extracellular matrix. Granulation tissue is the vascular, fibroblast-rich repair tissue that fills a wound during the proliferative phase.

Why is "Sheets of neutrophils and liquefactive necrosis" not the answer?

This describes acute suppurative injury, not repair.

Why is "Mature cartilage and bone" not the answer?

Cartilage and bone are not normal components of cutaneous granulation tissue.

Why is "Dense hypocellular collagen with no vessels" not the answer?

Dense, low-cellularity collagen characterises a mature scar.

What concept does this question test?

It tests Wound healing: granulation tissue in Pathology. It later remodels into a less vascular collagenous scar.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Wound healing: granulation tissue?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.