Renal pathology: nephritic syndrome: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Renal pathology: nephritic syndrome

Sample item

Which urinary sediment finding most strongly indicates glomerular bleeding in acute nephritic syndrome?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Red-cell casts

Red-cell casts form when erythrocytes leak through an injured glomerular filtration barrier and become trapped in Tamm-Horsfall protein. They strongly support glomerulonephritis.

Option by option

  • A. Fatty casts

    Fatty casts are associated with nephrotic syndrome.

  • B. White-cell casts only

    White-cell casts suggest pyelonephritis or interstitial nephritis.

  • C. Hyaline casts after exercise

    Hyaline casts can be nonspecific and occur with dehydration or exertion.

  • D. Red-cell casts (correct)

    Correct. Red-cell casts localise bleeding to the nephron, usually glomeruli.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is D, Red-cell casts. Red-cell casts form when erythrocytes leak through an injured glomerular filtration barrier and become trapped in Tamm-Horsfall protein.

Why is "Fatty casts" not the answer?

Fatty casts are associated with nephrotic syndrome.

Why is "White-cell casts only" not the answer?

White-cell casts suggest pyelonephritis or interstitial nephritis.

Why is "Hyaline casts after exercise" not the answer?

Hyaline casts can be nonspecific and occur with dehydration or exertion.

What concept does this question test?

It tests Renal pathology: nephritic syndrome in Pathology. They strongly support glomerulonephritis.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Renal pathology: nephritic syndrome?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.