MRI: multiple sclerosis: practice question

A Radiology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Radiology · MRI: multiple sclerosis

Sample item

Which MRI distribution is most characteristic of multiple sclerosis plaques?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Periventricular ovoid lesions oriented perpendicular to the ventricles

Multiple sclerosis commonly produces ovoid demyelinating lesions in characteristic locations including periventricular, juxtacortical, infratentorial, and spinal regions. Periventricular lesions may be oriented perpendicular to the ventricles.

Option by option

  • A. Isolated calcified basal ganglia lesion

    A solitary basal ganglia calcification is nonspecific and not the usual plaque pattern.

  • B. Periventricular ovoid lesions oriented perpendicular to the ventricles (correct)

    Correct. This distribution reflects typical demyelinating plaque morphology.

  • C. Diffuse skull thickening

    Skull thickening is not a typical MS finding.

  • D. Single epidural collection only

    An epidural collection suggests a different spinal or infectious process.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Radiology questions

Questions about this Radiology question

What is the answer to this Radiology question?

The best answer is B, Periventricular ovoid lesions oriented perpendicular to the ventricles. Multiple sclerosis commonly produces ovoid demyelinating lesions in characteristic locations including periventricular, juxtacortical, infratentorial, and spinal regions.

Why is "Isolated calcified basal ganglia lesion" not the answer?

A solitary basal ganglia calcification is nonspecific and not the usual plaque pattern.

Why is "Diffuse skull thickening" not the answer?

Skull thickening is not a typical MS finding.

Why is "Single epidural collection only" not the answer?

An epidural collection suggests a different spinal or infectious process.

What concept does this question test?

It tests MRI: multiple sclerosis in Radiology. Periventricular lesions may be oriented perpendicular to the ventricles.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study MRI: multiple sclerosis?

Learn signs with the image, and the disease they point to. Then use the flashcards and the other Radiology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.