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OBG · Obstetric medicine: gestational diabetes
Sample itemWhat is the principal fetal consequence of poorly controlled maternal hyperglycemia in late pregnancy?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Fetal hyperinsulinemia with macrosomia and neonatal hypoglycemia risk
Maternal glucose crosses the placenta, stimulating fetal insulin secretion. Fetal hyperinsulinemia promotes excessive growth and predisposes the newborn to hypoglycemia after birth when maternal glucose supply stops.
Option by option
A. Absent fetal growth
Poor control more often causes excessive, not absent, fetal growth.
B. Congenital deafness only
Congenital deafness is not the characteristic consequence.
C. Neural tube closure failure only
Neural tube defects are related to early pregnancy glycemic control but do not describe the main late-pregnancy mechanism here.
D. Fetal hyperinsulinemia with macrosomia and neonatal hypoglycemia risk (correct)
Correct. This explains both macrosomia and postnatal hypoglycemia.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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