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OBG · Obstetric medicine: RhD prophylaxis
Sample itemWhat is the purpose of anti-D immunoglobulin in an unsensitized RhD-negative pregnant patient carrying a potentially RhD-positive fetus?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Prevent maternal RhD alloimmunization
Anti-D immunoglobulin prevents maternal immune sensitization to fetal RhD-positive red cells after fetomaternal hemorrhage risk. It is prophylactic and does not reverse established alloimmunization.
Option by option
A. Prevent maternal RhD alloimmunization (correct)
Correct. It prevents formation of maternal anti-D antibodies.
B. Treat established fetal anemia directly
Established severe fetal anemia needs specialist fetal-medicine management.
C. Induce delivery
It is not an induction agent.
D. Increase fetal hemoglobin production
It does not stimulate fetal erythropoiesis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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