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Pediatrics · Nephrology: nephrotic syndrome
Sample itemA child presents with periorbital edema, ascites, heavy proteinuria, hypoalbuminemia, and hyperlipidemia. What is the most likely syndrome?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Nephrotic syndrome
Nephrotic syndrome is defined by heavy protein loss, low serum albumin, edema, and hyperlipidemia. Children require assessment for complications including infection and thrombosis.
Option by option
A. Urinary tract infection
UTI causes urinary symptoms and fever, not massive protein loss.
B. Diabetes insipidus
Diabetes insipidus causes polyuria and polydipsia with dilute urine.
C. Nephrotic syndrome (correct)
Correct. This protein-losing edema pattern is nephrotic syndrome.
D. Acute nephritic syndrome
Nephritic syndrome features hematuria, hypertension, and inflammatory glomerular injury.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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