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Pediatrics · Nephrology: poststreptococcal glomerulonephritis
Sample itemTwo weeks after impetigo, a child develops cola-colored urine, edema, hypertension, and reduced complement C3. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Poststreptococcal glomerulonephritis
Poststreptococcal glomerulonephritis is an immune-mediated nephritic syndrome following group A streptococcal infection. Hematuria, edema, hypertension, and low complement are typical.
Option by option
A. Hemolytic uremic syndrome
HUS follows diarrheal illness with anemia and thrombocytopenia.
B. Minimal change disease
Minimal change disease causes nephrotic rather than nephritic findings.
C. Vesicoureteric reflux
Vesicoureteric reflux predisposes to UTIs and renal scarring.
D. Poststreptococcal glomerulonephritis (correct)
Correct. The postinfectious nephritic pattern and low C3 fit PSGN.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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