Try it
Pharmacology · Analgesics
Sample itemWhy is naloxone given cautiously to opioid-dependent patients?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. It may precipitate acute withdrawal
Naloxone rapidly displaces opioids from receptors and can precipitate severe withdrawal in dependent patients, though ventilation remains the immediate priority.
Option by option
A. It may precipitate acute withdrawal (correct)
Correct: rapid antagonism can trigger withdrawal.
B. It increases opioid receptor activation
It blocks rather than activates opioid receptors.
C. It permanently blocks all pain pathways
Naloxone action is reversible and targeted.
D. It causes delayed renal failure
Renal failure is not the key acute concern.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.