Analgesics: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Analgesics

Sample item

Which opioid adverse effect is least likely to develop tolerance?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Constipation

Tolerance develops to many opioid effects, but constipation often persists because gut mu receptors remain inhibited without comparable adaptation.

Option by option

  • A. Constipation (correct)

    Correct: constipation commonly remains despite chronic exposure.

  • B. Sedation

    Sedation tolerance often develops.

  • C. Euphoria

    Euphoric effects can show tolerance.

  • D. Analgesia

    Analgesic tolerance can develop.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pharmacology questions

Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is A, Constipation. Tolerance develops to many opioid effects, but constipation often persists because gut mu receptors remain inhibited without comparable adaptation.

Why is "Sedation" not the answer?

Sedation tolerance often develops.

Why is "Euphoria" not the answer?

Euphoric effects can show tolerance.

Why is "Analgesia" not the answer?

Analgesic tolerance can develop.

What concept does this question test?

It tests Analgesics in Pharmacology. The correct option holds because: Correct: constipation commonly remains despite chronic exposure.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Analgesics?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.