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General Medicine · Gastroenterology: acute liver failure
Sample itemA patient with acute hepatitis develops INR elevation and new confusion without known cirrhosis. What syndrome is present?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Acute liver failure
Acute liver failure is acute hepatic injury with coagulopathy and encephalopathy in a person without established cirrhosis. It needs urgent specialist assessment because deterioration can be rapid.
Option by option
A. Simple viral gastroenteritis
Gastroenteritis does not cause synthetic liver failure.
B. Irritable bowel syndrome
IBS has no coagulopathy or encephalopathy.
C. Compensated chronic liver disease
Compensated chronic disease does not cause acute encephalopathy and coagulopathy by definition.
D. Acute liver failure (correct)
Correct. Coagulopathy plus encephalopathy defines acute liver failure in this setting.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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