Rheumatology: systemic sclerosis: practice question

A General Medicine question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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General Medicine · Rheumatology: systemic sclerosis

Sample item

A patient has Raynaud phenomenon, skin tightening of the fingers, telangiectasia, and dysphagia from reflux. What connective-tissue disease is most likely?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Systemic sclerosis

Systemic sclerosis causes fibrosis and vasculopathy, producing Raynaud phenomenon, sclerodactyly, telangiectasia, and gastrointestinal dysmotility. Internal organ involvement needs assessment.

Option by option

  • A. Systemic lupus erythematosus

    SLE has different features such as photosensitivity, serositis, and nephritis.

  • B. Systemic sclerosis (correct)

    Correct. The vascular and fibrotic features are characteristic.

  • C. Behcet disease

    Behcet disease causes recurrent oral/genital ulcers and uveitis.

  • D. Rheumatoid arthritis

    RA chiefly causes inflammatory synovitis.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this General Medicine question

What is the answer to this General Medicine question?

The best answer is B, Systemic sclerosis. Systemic sclerosis causes fibrosis and vasculopathy, producing Raynaud phenomenon, sclerodactyly, telangiectasia, and gastrointestinal dysmotility.

Why is "Systemic lupus erythematosus" not the answer?

SLE has different features such as photosensitivity, serositis, and nephritis.

Why is "Behcet disease" not the answer?

Behcet disease causes recurrent oral/genital ulcers and uveitis.

Why is "Rheumatoid arthritis" not the answer?

RA chiefly causes inflammatory synovitis.

What concept does this question test?

It tests Rheumatology: systemic sclerosis in General Medicine. Internal organ involvement needs assessment.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Rheumatology: systemic sclerosis?

For each disease know the classic presentation, the best test, and the first-line treatment. Then use the flashcards and the other General Medicine questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.