Rheumatology drugs: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Rheumatology drugs

Sample item

What is the main action of allopurinol?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Inhibit xanthine oxidase

Allopurinol lowers uric acid production by inhibiting xanthine oxidase and is used for long-term urate reduction, not acute analgesia.

Option by option

  • A. Inhibit xanthine oxidase (correct)

    Correct: xanthine oxidase inhibition reduces urate production.

  • B. Increase purine synthesis

    It does not increase purine synthesis.

  • C. Dissolve existing urate crystals directly

    It does not directly dissolve crystals immediately.

  • D. Activate cyclooxygenase

    Cyclooxygenase activation is not its action.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pharmacology questions

Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is A, Inhibit xanthine oxidase. Allopurinol lowers uric acid production by inhibiting xanthine oxidase and is used for long-term urate reduction, not acute analgesia.

Why is "Increase purine synthesis" not the answer?

It does not increase purine synthesis.

Why is "Dissolve existing urate crystals directly" not the answer?

It does not directly dissolve crystals immediately.

Why is "Activate cyclooxygenase" not the answer?

Cyclooxygenase activation is not its action.

What concept does this question test?

It tests Rheumatology drugs in Pharmacology. The correct option holds because: Correct: xanthine oxidase inhibition reduces urate production.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Rheumatology drugs?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.