Immunosuppressants: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Immunosuppressants

Sample item

What is the key toxicity of ciclosporin?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Nephrotoxicity

Ciclosporin inhibits calcineurin and T-cell activation but can cause dose-related nephrotoxicity, hypertension, tremor, and gingival hyperplasia.

Option by option

  • A. Tooth enamel loss

    Enamel loss is not characteristic.

  • B. Permanent mydriasis

    Mydriasis is not typical.

  • C. Severe iron deficiency

    Iron deficiency is not a key toxicity.

  • D. Nephrotoxicity (correct)

    Correct: renal vasoconstriction and nephrotoxicity are important.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pharmacology questions

Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is D, Nephrotoxicity. Ciclosporin inhibits calcineurin and T-cell activation but can cause dose-related nephrotoxicity, hypertension, tremor, and gingival hyperplasia.

Why is "Tooth enamel loss" not the answer?

Enamel loss is not characteristic.

Why is "Permanent mydriasis" not the answer?

Mydriasis is not typical.

Why is "Severe iron deficiency" not the answer?

Iron deficiency is not a key toxicity.

What concept does this question test?

It tests Immunosuppressants in Pharmacology. The correct option holds because: Correct: renal vasoconstriction and nephrotoxicity are important.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Immunosuppressants?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.