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General Medicine · Gastroenterology: spontaneous bacterial peritonitis
Sample itemA patient with cirrhosis and ascites has fever, worsening encephalopathy, and ascitic fluid neutrophil count of 320 cells/mm3. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Spontaneous bacterial peritonitis
Spontaneous bacterial peritonitis is diagnosed in ascites when the polymorphonuclear count is at least 250 cells/mm3, even if culture is negative. It requires prompt antibiotics and assessment for complications.
Option by option
A. Spontaneous bacterial peritonitis (correct)
Correct. The ascitic neutrophil count meets the diagnostic threshold.
B. Hepatorenal syndrome only
Hepatorenal syndrome is functional renal failure in advanced liver disease.
C. Uncomplicated portal hypertension
Portal hypertension alone does not cause neutrophilic infected ascites.
D. Acute pancreatitis
Pancreatitis has elevated pancreatic enzymes and different fluid findings.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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