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Pediatrics · Neonatology: hypoglycemia
Sample itemA jittery newborn of a mother with diabetes has poor feeding and low blood glucose. What is the likely mechanism?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Fetal hyperinsulinemia after loss of maternal glucose supply
Maternal hyperglycemia stimulates fetal pancreatic insulin production. After delivery, maternal glucose supply stops while neonatal hyperinsulinemia persists, causing hypoglycemia.
Option by option
A. Vitamin K deficiency
Vitamin K deficiency causes bleeding risk.
B. Excess cortisol production
Cortisol excess raises glucose availability.
C. Fetal hyperinsulinemia after loss of maternal glucose supply (correct)
Correct. Persistent fetal insulin drives postnatal glucose fall.
D. Congenital absence of insulin
Insulin absence causes hyperglycemia rather than hypoglycemia.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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