Hemodynamic disorders: disseminated intravascular coagulation: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Hemodynamic disorders: disseminated intravascular coagulation

Sample item

What is the central pathophysiologic feature of disseminated intravascular coagulation?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Widespread activation of coagulation with consumption of platelets and factors

DIC involves systemic thrombin generation that forms microthrombi and consumes platelets and coagulation factors, causing both thrombosis and bleeding. Sepsis, trauma, obstetric catastrophe, and malignancy are common triggers.

Option by option

  • A. Inherited deficiency of factor VIII only

    Factor VIII deficiency causes hemophilia A.

  • B. Isolated immune destruction of platelets

    Immune platelet destruction describes ITP.

  • C. Increased erythropoietin production

    Erythropoietin regulates red-cell production.

  • D. Widespread activation of coagulation with consumption of platelets and factors (correct)

    Correct. Consumptive coagulopathy explains the mixed thrombotic and bleeding state.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is D, Widespread activation of coagulation with consumption of platelets and factors. DIC involves systemic thrombin generation that forms microthrombi and consumes platelets and coagulation factors, causing both thrombosis and bleeding.

Why is "Inherited deficiency of factor VIII only" not the answer?

Factor VIII deficiency causes hemophilia A.

Why is "Isolated immune destruction of platelets" not the answer?

Immune platelet destruction describes ITP.

Why is "Increased erythropoietin production" not the answer?

Erythropoietin regulates red-cell production.

What concept does this question test?

It tests Hemodynamic disorders: disseminated intravascular coagulation in Pathology. Sepsis, trauma, obstetric catastrophe, and malignancy are common triggers.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Hemodynamic disorders: disseminated intravascular coagulation?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.