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General Medicine · Neurology
Sample itemA 72-year-old man has progressive gait disturbance with short magnetic steps, urinary urgency and memory decline over several months. CT shows enlarged ventricles without prominent cortical atrophy. Which treatment is most likely to help?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Ventriculoperitoneal shunt
Normal pressure hydrocephalus presents with the triad of gait apraxia, urinary incontinence and dementia, and imaging shows ventriculomegaly out of proportion to atrophy. Large-volume lumbar puncture can predict response. Shunting is the definitive treatment and gait usually improves first.
Option by option
A. Ventriculoperitoneal shunt (correct)
Correct. CSF diversion treats the potentially reversible dementia.
B. Anticoagulation
Anticoagulation has no role as there is no thromboembolic cause.
C. Levodopa-carbidopa
Levodopa gives little benefit because the gait disorder is not a nigrostriatal dopamine deficiency.
D. Donepezil alone
Cholinesterase inhibitors do not treat the cause and do not improve gait.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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