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General Medicine · Neurology
Sample itemA patient arrives 2 hours after the onset of right-sided weakness and aphasia. CT shows no haemorrhage. What is the most appropriate treatment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Intravenous alteplase (thrombolysis)
In acute ischaemic stroke, intravenous thrombolysis within 4.5 hours of onset (for eligible patients) after excluding haemorrhage improves outcome. Aspirin is given after the thrombolysis window decision. Heparin and steroids have no role in acute stroke.
Option by option
A. Heparin infusion
Heparin infusion increases bleeding risk without improving outcome in acute stroke.
B. Intravenous alteplase (thrombolysis) (correct)
Correct. Early thrombolysis restores perfusion to the salvageable penumbra.
C. Aspirin alone
Aspirin alone would be reserved for patients not eligible for thrombolysis.
D. Corticosteroids
Steroids do not help cerebral infarction.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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