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General Medicine · Nephrology
Sample itemRed blood cell casts in the urine most strongly suggest:
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Glomerulonephritis
Red cell casts form when red cells leak through damaged glomeruli and are moulded in the tubule. They indicate glomerular bleeding, as in nephritic syndrome. White cell casts suggest pyelonephritis or interstitial nephritis, fatty casts occur in nephrotic syndrome and hyaline casts can be normal.
Option by option
A. Glomerulonephritis (correct)
Correct. They are the urinary hallmark of glomerular inflammation.
B. Acute pyelonephritis
Pyelonephritis shows white cell casts.
C. Nephrotic syndrome
Nephrotic syndrome shows fatty casts and oval fat bodies.
D. Dehydration
Dehydration may increase hyaline casts only.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.