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General Medicine · Cardiology
Sample itemA 30-year-old man has sharp pleuritic central chest pain that eases on sitting forward, two weeks after a viral illness. ECG shows widespread concave ST elevation with PR depression. What is the best treatment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. High-dose NSAID or aspirin with colchicine
Acute pericarditis is diagnosed by pleuritic pain, a friction rub, diffuse ST elevation with PR depression and a pericardial effusion. First-line therapy is an NSAID or aspirin plus colchicine, which lowers recurrence. Anticoagulants and thrombolytics increase the risk of haemopericardium.
Option by option
A. Intravenous heparin infusion
Heparin does not treat pericarditis and may cause bleeding into the pericardium.
B. High-dose NSAID or aspirin with colchicine (correct)
Correct. NSAIDs with colchicine are first-line for acute pericarditis.
C. Thrombolysis with alteplase
Thrombolysis is for ST elevation myocardial infarction and risks haemopericardium here.
D. Primary angioplasty
Primary angioplasty is not indicated since the ST elevation is diffuse and non-coronary.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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