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General Medicine · Infectious diseases: neurocysticercosis
Sample itemA 28-year-old man from a pig-rearing community has a first generalised seizure. CT shows two small cystic lesions in the cerebral cortex, each with an eccentric dot-like scolex, and no hydrocephalus. Fundus examination is normal. What is the most appropriate management?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Albendazole with corticosteroids and an antiepileptic drug
Viable parenchymal neurocysticercosis is treated with albendazole, often with praziquantel in multiple cysts, together with corticosteroids to blunt the inflammatory reaction as the larvae die, and an antiepileptic drug for seizures. The eyes are examined first because treating intraocular cysts can cause blindness. Surgery is reserved for intraventricular or obstructive lesions.
Option by option
A. Empirical antituberculosis therapy
A cyst with a visible scolex is characteristic of cysticercosis rather than a tuberculoma.
B. Albendazole with corticosteroids and an antiepileptic drug (correct)
Cysticidal drug cover with steroid and antiepileptic therapy is the standard regimen.
C. Albendazole alone without steroids
Antiparasitic therapy without steroids risks a severe inflammatory reaction and worsened seizures.
D. Surgical excision of both cysts
Small parenchymal cysts do not need surgery.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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