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General Medicine · Neurology: lateral medullary syndrome
Sample itemA 60-year-old hypertensive man has sudden vertigo, vomiting, hoarseness and dysphagia. Examination shows loss of pain and temperature sensation on the left side of the face and right half of the body, left Horner syndrome and left limb ataxia, with normal limb strength. Which vessel is occluded?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Left posterior inferior cerebellar artery or left vertebral artery
Lateral medullary (Wallenberg) syndrome involves the spinal trigeminal nucleus (ipsilateral facial pain and temperature loss), the spinothalamic tract (contralateral body), nucleus ambiguus (hoarseness, dysphagia), sympathetic fibres (Horner) and the inferior cerebellar peduncle (ataxia). Pyramidal fibres are spared. The usual cause is occlusion of the vertebral or posterior inferior cerebellar artery.
Option by option
A. Basilar artery perforating branches
Basilar perforator occlusion causes pontine weakness and locked-in states, which are absent here.
B. Anterior spinal artery supplying the medulla
Anterior spinal artery occlusion causes medial medullary syndrome with contralateral hemiparesis and tongue deviation.
C. Left posterior inferior cerebellar artery or left vertebral artery (correct)
Correct. The deficits match the territory of the posterior inferior cerebellar or vertebral artery.
D. Left anterior inferior cerebellar artery
AICA occlusion causes a lateral pontine syndrome with facial paralysis and deafness.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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