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General Medicine · Cardiology: constrictive pericarditis versus restrictive cardiomyopathy
Sample itemA 45-year-old farmer who had tuberculous pericarditis years ago has progressive ankle swelling and ascites. Jugular venous pressure rises on inspiration, an early diastolic sound is heard, and ejection fraction is normal. Which echocardiographic finding best favours constrictive pericarditis over restrictive cardiomyopathy?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Septal shift toward the left ventricle during inspiration, showing ventricular interdependence
In constriction the rigid pericardium isolates the heart from intrathoracic pressure changes, so inspiration increases right ventricular filling at the expense of the left and shifts the septum leftward. This exaggerated respiratory ventricular interdependence is the key discriminator. Preserved ejection fraction, a plethoric IVC and raised venous pressure occur in both conditions, whereas marked atrial enlargement with thick walls suggests an infiltrative restrictive process such as amyloid.
Option by option
A. Dilated inferior vena cava without inspiratory collapse
A dilated non-collapsing IVC reflects raised right atrial pressure, which is present in both disorders.
B. Septal shift toward the left ventricle during inspiration, showing ventricular interdependence (correct)
Respiratory septal shift with ventricular interdependence is characteristic of constriction and is absent in restriction.
C. Marked biatrial enlargement with thickened ventricular walls
Biatrial enlargement with thick walls points to restrictive (infiltrative) cardiomyopathy, not constriction.
D. Preserved ejection fraction with impaired diastolic filling
Both conditions show preserved systolic function with diastolic filling impairment, so this does not separate them.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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