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Dermatology · Infections: bacterial, viral, fungal, parasitic: cutaneous diphtheria
Sample itemA homeless man has a chronic punched-out ulcer on the shin with a grey-brown adherent membrane that has not healed for weeks. A smear from the edge shows pleomorphic Gram-positive bacilli lying in angular, Chinese-letter arrangements. Which organism is responsible?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Corynebacterium diphtheriae
Cutaneous diphtheria presents as a chronic shallow ulcer with a grey membrane, mainly in poor and crowded settings and in the tropics. Club-shaped Gram-positive bacilli in palisades or Chinese letters are typical. The ulcer is also a reservoir for respiratory spread, so the patient needs antibiotics and contacts need vaccination checks.
Option by option
A. Pseudomonas aeruginosa
Pseudomonas is a Gram-negative bacillus and gives green exudate and a pungent odour.
B. Corynebacterium diphtheriae (correct)
Correct. Pleomorphic club-shaped bacilli in Chinese-letter arrangement identify Corynebacterium diphtheriae.
C. Bacillus anthracis
Anthrax gives a painless black eschar with marked oedema, and its bacilli are large boxcar rods in chains.
D. Staphylococcus aureus
Staphylococci appear as Gram-positive cocci in clusters, not as angular bacilli.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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