Vesiculobullous disorders: polymorphic eruption of pregnancy: practice question

A Dermatology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Dermatology · Vesiculobullous disorders: polymorphic eruption of pregnancy

Sample item

A primigravida in the third trimester develops intensely itchy urticarial papules that start within abdominal striae and spare the periumbilical skin, with no blisters. Which statement about her condition is correct?

AIt recurs in almost every later pregnancyBIt frequently causes stillbirth and needs early deliveryCIt shows linear C3 along the basement membraneDIt is benign, carries no fetal risk, and usually resolves within weeks of delivery

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. It is benign, carries no fetal risk, and usually resolves within weeks of delivery

Polymorphic eruption of pregnancy (PUPPP) is a common pruritic eruption of primigravidae, starting in abdominal striae with periumbilical sparing. It carries no maternal or fetal risk, usually clears within about 4 weeks of delivery, and seldom recurs. Treatment is emollients, topical steroids and antihistamines.

Option by option

A. It recurs in almost every later pregnancy
Recurrence is unusual, in contrast with pemphigoid gestationis.
B. It frequently causes stillbirth and needs early delivery
Stillbirth risk is a concern in intrahepatic cholestasis of pregnancy, not in this eruption.
C. It shows linear C3 along the basement membrane
Linear C3 at the basement membrane is the immunofluorescence finding of pemphigoid gestationis.
D. It is benign, carries no fetal risk, and usually resolves within weeks of delivery (correct)
Correct. It is benign with no fetal risk and resolves after delivery.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

Questions about this Dermatology question

What is the answer to this Dermatology question?

The best answer is D, It is benign, carries no fetal risk, and usually resolves within weeks of delivery. Polymorphic eruption of pregnancy (PUPPP) is a common pruritic eruption of primigravidae, starting in abdominal striae with periumbilical sparing.

Why is "It recurs in almost every later pregnancy" not the answer?

Recurrence is unusual, in contrast with pemphigoid gestationis.

Why is "It frequently causes stillbirth and needs early delivery" not the answer?

Stillbirth risk is a concern in intrahepatic cholestasis of pregnancy, not in this eruption.

Why is "It shows linear C3 along the basement membrane" not the answer?

Linear C3 at the basement membrane is the immunofluorescence finding of pemphigoid gestationis.

What concept does this question test?

It tests Vesiculobullous disorders: polymorphic eruption of pregnancy in Dermatology. It carries no maternal or fetal risk, usually clears within about 4 weeks of delivery, and seldom recurs. Treatment is emollients, topical steroids and antihistamines.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Vesiculobullous disorders: polymorphic eruption of pregnancy?

Learn each condition by its primary lesion, site and signature sign. Then use the flashcards and the other Dermatology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.