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Ophthalmology · Neuro-ophthalmology and pupils: rhino-orbital mucormycosis
Sample itemA 55-year-old man with uncontrolled diabetes and ketoacidosis has facial pain, unilateral proptosis, ptosis, complete ophthalmoplegia, loss of vision and a black necrotic eschar over the nasal turbinate. What is the likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Rhino-orbital mucormycosis
Rhino-orbital mucormycosis is an angioinvasive fungal infection seen in ketoacidosis and other immunocompromised states. It invades vessels, producing black necrotic tissue, orbital apex syndrome and rapid vision loss.
Option by option
A. Rhino-orbital mucormycosis (correct)
Correct. Ketoacidosis with a black eschar and orbital apex signs is mucormycosis.
B. Tolosa-Hunt syndrome
Tolosa-Hunt is a painful steroid-responsive granulomatous cavernous sinus inflammation without necrosis.
C. Bacterial orbital cellulitis
Bacterial orbital cellulitis is purulent and does not cause a black necrotic eschar with early ophthalmoplegia.
D. Thyroid orbitopathy
Thyroid orbitopathy gives proptosis and lid retraction without necrosis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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