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Radiology · Abdominal and GI imaging: mesenteric lymphoma
Sample itemA patient with fever, night sweats and abdominal discomfort has CT showing bulky confluent mesenteric nodes that surround and elevate the mesenteric vessels without narrowing them. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Lymphoma
In lymphoma the nodes envelop the mesenteric fat and vessels, called the sandwich sign, but do not invade or narrow them. A carcinoid mesenteric mass shows calcification and a desmoplastic reaction that tethers and kinks the vessels. Retroperitoneal fibrosis is a plaque around the aorta, not mesenteric nodes.
Option by option
A. Sclerosing mesenteritis
Sclerosing mesenteritis shows a fibrotic mass with a fat halo, usually in a well patient.
B. Carcinoid tumour
A carcinoid mass is desmoplastic, often calcified and retracts or narrows the vessels.
C. Lymphoma (correct)
Correct. Bulky nodes enveloping unnarrowed vessels is the lymphoma pattern.
D. Retroperitoneal fibrosis
Retroperitoneal fibrosis forms a plaque around the aorta and ureters.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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