Try it
Dermatology · Infections: bacterial, viral, fungal, parasitic: purpura fulminans in a febrile child
Sample itemA 6-year-old has had fever and vomiting for a few hours, and now has non-blanching purpuric spots spreading over the trunk and limbs, cold peripheries and a blood pressure of 80/50 mmHg. What is the most appropriate immediate action?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Give intravenous ceftriaxone at once
Fever with rapidly spreading non-blanching purpura and shock suggests meningococcaemia, a time-critical emergency. A third-generation cephalosporin should be given immediately after drawing blood cultures, with fluid resuscitation, and must not be delayed for lumbar puncture, which is unsafe in shock.
Option by option
A. Observe and repeat the blood count in 24 hours
Waiting 24 hours risks death, since meningococcal sepsis progresses within hours.
B. Do a lumbar puncture before any treatment
Lumbar puncture in a shocked child is unsafe and delays life-saving antibiotics.
C. Give intravenous ceftriaxone at once (correct)
Correct. Parenteral ceftriaxone without delay is the priority, with fluids and supportive care.
D. Start oral penicillin V and review tomorrow
Oral therapy is inadequate for septicaemia with shock.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
More Dermatology questions
- Blistering disordersA patient has flaccid blisters that rupture easily and a positive Nikolsky sign. Which c…
- LeprosyIn which type of leprosy is the lepromin test strongly positive?
- Pigmentary disordersA man has well-demarcated chalk-white macules on his hands and around his mouth. A skin…
- Drug reactionsWhich of the following drugs is a well-recognised trigger of Stevens–Johnson syndrome an…