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Dermatology · STI: treatment of chancroid
Sample itemA man has multiple soft, painful genital ulcers with a tender inguinal bubo. Which single-dose regimen treats chancroid?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Azithromycin 1 g orally
A single oral dose of azithromycin 1 g cures chancroid, and ceftriaxone 250 mg intramuscularly as a single dose is an alternative. Penicillin does not cover Haemophilus ducreyi.
Option by option
A. Azithromycin 1 g orally (correct)
Correct. Single-dose azithromycin is effective for chancroid.
B. Doxycycline 200 mg orally
A single dose of doxycycline is not a recognised chancroid regimen.
C. Metronidazole 2 g orally
Metronidazole treats trichomoniasis and bacterial vaginosis, not chancroid.
D. Benzathine penicillin G 2.4 million units intramuscularly
Benzathine penicillin treats syphilis, and H. ducreyi is not reliably susceptible to it.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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