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Dermatology · STI: meningovascular syphilis
Sample itemA 38-year-old man treated inadequately for a genital sore years ago develops sudden hemiparesis. CSF shows lymphocytic pleocytosis, raised protein and a reactive VDRL. Which form of neurosyphilis is this?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Meningovascular syphilis
Meningovascular syphilis is an endarteritis of cerebral vessels that causes strokes in young adults, typically 5 to 10 years after infection. Tabes and general paresis appear decades later.
Option by option
A. Tabes dorsalis
Tabes dorsalis causes lightning pains, ataxia and posterior column loss, not an acute stroke.
B. Cerebral gumma
A cerebral gumma is a mass lesion and is rare.
C. General paresis
General paresis causes progressive dementia and behavioural change 15 to 20 years after infection.
D. Meningovascular syphilis (correct)
Correct. Stroke in a young adult with an inflammatory CSF and reactive VDRL fits meningovascular syphilis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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