Drug reactions: toxic epidermal necrolysis eye care: practice question

A Dermatology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Dermatology · Drug reactions: toxic epidermal necrolysis eye care

Sample item

A patient with toxic epidermal necrolysis has conjunctival erosions and early pseudomembrane formation. Which measure best reduces long-term ocular sequelae?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Early ophthalmology review with lysis of adhesions and lubrication, with amniotic membrane in severe cases

Ocular involvement occurs in most SJS/TEN patients and can cause symblepharon, dry eye and blindness. Daily ophthalmological assessment, preservative-free lubricants, topical steroid, breaking adhesions and amniotic membrane grafts in severe acute disease limit sequelae.

Option by option

  • A. Eye patching with tight bandaging

    Tight patching causes friction and damage to fragile conjunctiva.

  • B. Delaying ophthalmology review until re-epithelialisation

    Waiting for healing allows adhesions and scarring to form.

  • C. Daily systemic antibiotics to prevent keratitis

    Routine systemic antibiotics do not prevent ocular sequelae of mucosal necrosis.

  • D. Early ophthalmology review with lysis of adhesions and lubrication, with amniotic membrane in severe cases (correct)

    Correct. Early specialist care and mechanical prevention of adhesions reduce chronic ocular damage.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Dermatology question

What is the answer to this Dermatology question?

The best answer is D, Early ophthalmology review with lysis of adhesions and lubrication, with amniotic membrane in severe cases. Ocular involvement occurs in most SJS/TEN patients and can cause symblepharon, dry eye and blindness.

Why is "Eye patching with tight bandaging" not the answer?

Tight patching causes friction and damage to fragile conjunctiva.

Why is "Delaying ophthalmology review until re-epithelialisation" not the answer?

Waiting for healing allows adhesions and scarring to form.

Why is "Daily systemic antibiotics to prevent keratitis" not the answer?

Routine systemic antibiotics do not prevent ocular sequelae of mucosal necrosis.

What concept does this question test?

It tests Drug reactions: toxic epidermal necrolysis eye care in Dermatology. Daily ophthalmological assessment, preservative-free lubricants, topical steroid, breaking adhesions and amniotic membrane grafts in severe acute disease limit sequelae.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Drug reactions: toxic epidermal necrolysis eye care?

Learn each condition by its primary lesion, site and signature sign. Then use the flashcards and the other Dermatology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.