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ENT · Head and neck tumours: occupational sinonasal carcinoma
Sample itemA 52-year-old man worked for decades in a nickel refinery. Which sinonasal malignancy is he at increased risk of?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Squamous cell carcinoma
Nickel exposure is associated with sinonasal squamous cell carcinoma. Hardwood and leather dust are linked instead to ethmoid adenocarcinoma. Melanoma and esthesioneuroblastoma have no recognised occupational association.
Option by option
A. Esthesioneuroblastoma
Esthesioneuroblastoma has no occupational link.
B. Squamous cell carcinoma (correct)
Correct. Nickel refining is linked with sinonasal squamous carcinoma.
C. Mucosal melanoma
Mucosal melanoma has no occupational link.
D. Adenocarcinoma of the ethmoid
Ethmoid adenocarcinoma is linked to hardwood and leather dust.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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