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General Medicine · Cardiology: non-compressible vessels and ankle-brachial index
Sample itemA 63-year-old man with long-standing diabetes and chronic kidney disease has calf pain after 200 metres of walking that settles on rest. Foot pulses are not palpable, but the ankle-brachial index is 1.5. What is the best next step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Measure the toe-brachial index
An ankle-brachial index above 1.4 suggests calcified, non-compressible arteries, as seen in diabetes and renal disease, and falsely excludes arterial disease. Digital arteries are rarely calcified, so the toe-brachial index gives a more reliable measure of perfusion.
Option by option
A. Request nerve conduction studies
Nerve studies address a neuropathic cause, which does not fit exertional pain that eases on rest.
B. Accept the index as normal and reassure
A value above 1.4 is not normal and cannot be used to exclude peripheral arterial disease.
C. Measure the toe-brachial index (correct)
Correct. Calcified ankle vessels give a falsely high index; toe pressures avoid this error.
D. Start an exercise programme for neuropathy
The history of calf pain relieved by rest fits claudication rather than neuropathy.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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