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General Medicine · Respiratory medicine: Meigs syndrome
Sample itemA 48-year-old woman has weight loss, abdominal distension and a right-sided pleural effusion. Imaging shows a solid ovarian tumour that is benign on histology. Both the ascites and the effusion resolve completely after the tumour is removed. Which diagnosis fits?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Meigs syndrome
Meigs syndrome is the triad of a benign ovarian tumour (usually a fibroma), ascites and a pleural effusion that resolve after resection. The fluid reaches the chest through diaphragmatic defects and lymphatics.
Option by option
A. Meigs syndrome (correct)
Correct. A benign ovarian tumour with ascites and effusion that resolves after resection is Meigs syndrome.
B. Krukenberg tumour from a gastric primary
A Krukenberg tumour is a malignant metastasis and the fluid would not clear after removal.
C. Tuberculous peritonitis with effusion
Tuberculous peritonitis would not resolve after removing an ovarian tumour.
D. Ovarian hyperstimulation syndrome
Ovarian hyperstimulation follows gonadotropin treatment, with bilateral enlarged ovaries.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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