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General Medicine · Endocrinology and diabetes: craniopharyngioma
Sample itemA 9-year-old boy has headache, growth failure and bitemporal visual field loss. MRI shows a partly cystic, calcified suprasellar mass. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Craniopharyngioma
Craniopharyngioma arises from Rathke pouch remnants and is the commonest suprasellar mass in children, with cysts and calcification on imaging. It causes visual field defects, hypopituitarism and diabetes insipidus.
Option by option
A. Optic pathway glioma
Optic glioma enlarges the optic nerves or chiasm and is not cystic or calcified.
B. Craniopharyngioma (correct)
Correct. A calcified, cystic suprasellar mass in a child is typical.
C. Medulloblastoma
Medulloblastoma arises in the posterior fossa.
D. Prolactinoma
Prolactinoma is intrasellar, uncommon in young boys and rarely calcified.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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