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General Medicine · Infectious diseases: necrotising fasciitis
Sample itemA 55-year-old diabetic man has a rapidly spreading red, swollen leg with severe pain out of proportion to the visible changes. He is hypotensive and a few areas of skin are dusky with bullae. What is the most important next step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Urgent surgical exploration and debridement with broad-spectrum antibiotics
Pain out of proportion, rapid spread, bullae and shock suggest necrotising fasciitis. Survival depends on early surgery to remove infected tissue, together with broad-spectrum antibiotics covering anaerobes, streptococci and Gram-negative organisms.
Option by option
A. MRI of the leg before any intervention
Imaging delays surgery in a clinically obvious case.
B. Oral antibiotics and review after 48 hours
Oral antibiotics with a delayed review would allow a lethal infection to spread.
C. Urgent surgical exploration and debridement with broad-spectrum antibiotics (correct)
Correct. Early debridement is the definitive and life-saving step.
D. Compression bandaging and elevation
Compression and elevation treat venous or lymphatic oedema, not this infection.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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