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General Medicine · Infectious diseases: post-kala-azar dermal leishmaniasis
Sample itemA 25-year-old man from Bihar was treated for kala-azar two years ago. He now has hypopigmented macules and nodules over the face and trunk without sensory loss. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Post-kala-azar dermal leishmaniasis
Post-kala-azar dermal leishmaniasis appears months to years after visceral leishmaniasis, with hypopigmented macules or nodules mainly on the face. Skin sensation is preserved, unlike in leprosy, and the patients act as a reservoir of infection.
Option by option
A. Tuberculoid leprosy
Tuberculoid leprosy produces anaesthetic lesions with nerve thickening.
B. Vitiligo
Vitiligo gives depigmented patches without nodules or a link to kala-azar.
C. Post-kala-azar dermal leishmaniasis (correct)
Correct. A past kala-azar with new facial macules and nodules fits this late dermal form.
D. Pityriasis versicolor
Pityriasis versicolor causes scaly patches without nodules.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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