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General Medicine · Rheumatology: oligoarticular juvenile arthritis and uveitis
Sample itemA 3-year-old girl has had a swollen, non-painful knee for 3 months without fever or rash. ANA is positive and rheumatoid factor is negative. Which complication should be screened for with regular slit-lamp examination?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Chronic anterior uveitis
Young girls with oligoarticular juvenile idiopathic arthritis who are ANA positive have a high risk of chronic anterior uveitis, which is often asymptomatic and can cause blindness. Regular slit-lamp screening is mandatory.
Option by option
A. Retinal detachment
Retinal detachment is not a recognised complication of this arthritis.
B. Chronic anterior uveitis (correct)
Correct. Silent anterior uveitis is the major threat to vision in ANA-positive oligoarticular disease.
C. Optic neuritis
Optic neuritis is a feature of demyelinating disease, not of juvenile arthritis.
D. Keratoconjunctivitis sicca
Dry eye from sicca is a feature of Sjogren syndrome.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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