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OBG · Complications of pregnancy: contraindication to tocolysis
Sample itemA woman at 30 weeks with threatened preterm labour is being considered for tocolysis to allow antenatal corticosteroids to act. In which situation should tocolysis be avoided?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Clinical chorioamnionitis
Tocolysis is contraindicated when continuing the pregnancy is dangerous, as in intrauterine infection, placental abruption, severe pre-eclampsia, fetal death or a lethal anomaly, and in fetal compromise. Its purpose is to gain 48 hours for steroids and transfer, which is a valid indication.
Option by option
A. Intact membranes with 2 cm dilatation
Intact membranes with early dilatation is the typical situation in which tocolysis is considered.
B. Twin pregnancy
Twin pregnancy is not a contraindication, although risk of pulmonary oedema is higher.
C. A need to transfer to a centre with a neonatal unit
Gaining time for in-utero transfer is one of the accepted purposes of tocolysis.
D. Clinical chorioamnionitis (correct)
Correct. Continuing a pregnancy with intra-amniotic infection is harmful, so tocolysis is withheld and delivery is planned.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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