Hypertensive disorders: early-onset pre-eclampsia: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Hypertensive disorders: early-onset pre-eclampsia

Sample item

Which feature is more typical of early-onset pre-eclampsia (before 34 weeks) than of late-onset disease?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Abnormal uterine artery Doppler and fetal growth restriction

Early-onset disease is strongly linked to defective placentation, abnormal uterine artery Doppler, growth restriction and worse maternal outcomes. Late-onset disease is more associated with maternal constitutional factors such as obesity and a normal-sized fetus.

Option by option

  • A. Abnormal uterine artery Doppler and fetal growth restriction (correct)

    Correct. Placental origin explains abnormal Doppler and growth restriction.

  • B. Normal fetal growth with macrosomia

    Macrosomia is more typical of diabetes and late-onset cases.

  • C. Normal placental histology with a large placenta

    A large placenta with normal histology fits late-onset disease or other conditions.

  • D. Predominantly maternal metabolic risk and a normal placenta

    Maternal metabolic predisposition with a normal placenta describes late-onset disease.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More OBG questions

Questions about this OBG question

What is the answer to this OBG question?

The best answer is A, Abnormal uterine artery Doppler and fetal growth restriction. Early-onset disease is strongly linked to defective placentation, abnormal uterine artery Doppler, growth restriction and worse maternal outcomes.

Why is "Normal fetal growth with macrosomia" not the answer?

Macrosomia is more typical of diabetes and late-onset cases.

Why is "Normal placental histology with a large placenta" not the answer?

A large placenta with normal histology fits late-onset disease or other conditions.

Why is "Predominantly maternal metabolic risk and a normal placenta" not the answer?

Maternal metabolic predisposition with a normal placenta describes late-onset disease.

What concept does this question test?

It tests Hypertensive disorders: early-onset pre-eclampsia in OBG. Late-onset disease is more associated with maternal constitutional factors such as obesity and a normal-sized fetus.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Hypertensive disorders: early-onset pre-eclampsia?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.