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OBG · Hypertensive disorders: pre-eclampsia before 20 weeks
Sample itemA woman at 14 weeks has blood pressure 160/110 mmHg, proteinuria, a uterus larger than dates and vomiting. Which underlying condition should be suspected?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Hydatidiform mole
Pre-eclampsia before 20 weeks is unusual and suggests a molar pregnancy, triploidy or antiphospholipid syndrome. An enlarged uterus, vomiting and early hypertension with proteinuria are classic for a molar pregnancy, and ultrasound confirms it.
Option by option
A. Hydatidiform mole (correct)
Correct. Early severe hypertension with a large uterus suggests a mole.
B. Renal artery stenosis
Renal artery stenosis does not explain the uterine size or vomiting.
C. Chronic essential hypertension
Essential hypertension would not explain the large uterus and new proteinuria.
D. Twin pregnancy
Twin pregnancy raises the risk of pre-eclampsia, but later and not at 14 weeks.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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