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OBG · Hypertensive disorders: avoiding abrupt fall in pressure
Sample itemWhy should blood pressure in severe pre-eclampsia be lowered gradually, not precipitously?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. The uteroplacental circulation lacks autoregulation, so a sudden fall causes fetal distress
The uteroplacental bed is maximally dilated and cannot autoregulate, so perfusion depends on maternal pressure. A sharp fall reduces placental blood flow and can cause fetal hypoxia and bradycardia. The aim is a gradual, controlled reduction.
Option by option
A. Rapid lowering worsens proteinuria permanently
Rapid lowering does not permanently worsen proteinuria.
B. The uteroplacental circulation lacks autoregulation, so a sudden fall causes fetal distress (correct)
Correct. Placental perfusion depends on maternal pressure, so a rapid fall endangers the fetus.
C. A sudden fall causes magnesium to be excreted rapidly
Blood pressure changes do not change magnesium excretion.
D. Rapid lowering increases the risk of placenta praevia
Placenta praevia is a placental location and is not related to blood pressure changes.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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