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OBG · Hypertensive disorders: choice of drug in asthma
Sample itemA woman at 33 weeks with bronchial asthma has a blood pressure of 168/112 mmHg and needs urgent oral treatment. Which choice is better?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Oral nifedipine
Labetalol and other beta-blockers can precipitate bronchospasm in asthma, so a calcium channel blocker is preferred. Nifedipine acts quickly orally. Nitroprusside is avoided in pregnancy except as a last resort because of the risk of fetal cyanide toxicity.
Option by option
A. Oral propranolol
Propranolol is a non-selective beta-blocker and is more likely to worsen asthma.
B. Intravenous sodium nitroprusside
Nitroprusside is a last resort because of cyanide toxicity to the fetus.
C. Oral nifedipine (correct)
Correct. Nifedipine lowers pressure without bronchospasm.
D. Intravenous labetalol
Labetalol has beta-blocking action and can trigger bronchospasm in asthma.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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