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OBG · Gynaecological endocrinology: Herlyn-Werner-Wunderlich syndrome
Sample itemA 13-year-old has cyclic pelvic pain, a tender paravaginal mass and regular menses from one side. Imaging shows a double uterus with an obstructed hemivagina. Which associated anomaly should be sought?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Ipsilateral renal agenesis
Uterus didelphys with an obstructed hemivagina is typically accompanied by ipsilateral renal agenesis (Herlyn-Werner-Wunderlich syndrome). Menses continue from the patent side while blood collects in the obstructed side, so renal imaging is needed.
Option by option
A. Ipsilateral renal agenesis (correct)
Correct. The obstructed side is classically associated with absent ipsilateral kidney.
B. Contralateral horseshoe kidney
Horseshoe kidney is a fusion anomaly not specific to this Mullerian disorder.
C. Spina bifida
Spina bifida is not associated with this Mullerian anomaly.
D. Coarctation of the aorta
Coarctation of the aorta is associated with Turner syndrome.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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