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Psychiatry · Organic mental disorders: prosopagnosia
Sample itemAfter a stroke, a 60-year-old woman cannot recognise her husband's face or her own face in a mirror, though she knows him at once when he speaks. Her visual acuity is normal. Which brain region is typically damaged?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Bilateral fusiform gyri in the inferomedial occipitotemporal cortex
Prosopagnosia is a visual agnosia for faces, usually from bilateral (or right-sided) lesions of the fusiform face area in the inferomedial occipitotemporal region. Recognition through voice, gait or clothing is preserved.
Option by option
A. Dominant inferior frontal gyrus
The dominant inferior frontal gyrus contains Broca area, concerned with speech production.
B. Bilateral mamillary bodies
Mamillary body damage causes amnesia, not an inability to recognise faces.
C. Bilateral fusiform gyri in the inferomedial occipitotemporal cortex (correct)
Correct. The fusiform face area underlies recognition of faces.
D. Dominant angular gyrus
The dominant angular gyrus is linked with alexia with agraphia and Gerstmann syndrome.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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